City workers and local artists painted the words Black Lives Matter in enormous bright yellow letters on the street leading to the White House, a highly visible sign of the District of Columbia's embrace of a protest movement that has put it even further at odds with President Donald Trump.

DC Mayor Muriel Bowser said after the mural was completed on Friday (US time) that it was intended to send a message of support and solidarity to Americans outraged over the killing of George Floyd by police in Minneapolis.

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"There is a lot of distrust of police and the government. There are people who are craving to be heard and to be seen and to have their humanity recognised," the mayor said. "We had the opportunity to send that message loud and clear on a very important street in our city."

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The Washington Monument and the White House are visible behind the words Black Lives Matter sign that has been painted in bright yellow letters. Photo / AP
The Washington Monument and the White House are visible behind the words Black Lives Matter sign that has been painted in bright yellow letters. Photo / AP

The letters and an image of the city's flag stretch across 16th St for two blocks. The mural ends near St John's Episcopal Church, where Trump staged a photo-op on Monday after officers in riot gear fired tear gas and charged demonstrators to make way for the president and his entourage.

A sign now identifies that section of 16th St near the White House as "Black Lives Matter Plaza".

Bower has verbally clashed with the Trump administration over the handling of the protests. The mayor has complained about the heavy-handed federal response and called for the removal of out-of-state National Guard troops.

City workers and activists paint the words Black Lives Matter in enormous bright yellow letters on the the street leading to the White House. Photo / AP
City workers and activists paint the words Black Lives Matter in enormous bright yellow letters on the the street leading to the White House. Photo / AP

She says their differences highlight the need for DC to be a state and have more control over its affairs. They may also reflect the fact Trump is deeply unpopular in the district, where Hillary Clinton won about 90 per cent of the vote in the 2016 presidential election.

While not addressing the painted mural, Trump continued his attacks on Bowser in tweets on Friday.

District of Columbia Mayor Muriel Bowser stands on the rooftop of the Hay Adams Hotel near the White House. Photo / AP
District of Columbia Mayor Muriel Bowser stands on the rooftop of the Hay Adams Hotel near the White House. Photo / AP

"The incompetent Mayor of Washington, D.C., @Mayor Bowser, who's budget is totally out of control and is constantly coming back to us for 'handouts,' is now fighting with the National Guard, who saved her from great embarrassment over the last number of nights," he tweeted. "If she doesn't treat these men and women well, then we'll bring in a different group of men and women!"

She shrugged off his criticism. "You know that thing about the pot and the kettle," the mayor said at a news conference.

Donald Trump stands in front church holding bible after threatening military action against protesters. Video / NBC News

The local chapter of Black Lives Matter said it did not support painting the street and took a swipe at Bowser. "This is performative and a distraction from her active counter organising to our demands to decrease the police budget and invest in the community," it said on Twitter.

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Demonstrators protest near the White House. Photo / AP
Demonstrators protest near the White House. Photo / AP

On Thursday, as the protests remained peaceful, Bowser ended a curfew imposed after people damaged buildings and broke into businesses over the weekend and Monday. A large demonstration is expected in the city on Saturday, and the city has not yet decided whether the curfew will be reinstated.

The mayor tweeted out a letter from House Speaker Nancy Pelosi, who wrote to the president to express alarm that peaceful protesters were being confronted by heavily armed federal agents and officers, many of them with their identities and agencies obscured.

Law enforcement personnel dressed in riot gear used tear gas to disperse protesters near the White House as a curfew neared in the nation's capital. Video / AP

There are thousands of members of the National Guard along with officers and agents from numerous agencies deployed around Washington in case of civil unrest.

- AP