Port Hedland in Western Australia is on red alert as the category three Severe Tropical Cyclone Rusty moves slowly towards the coast.
Port Hedland residents have been urged to leave their homes immediately.
Emergency shelters have been opened at the Andrew McLaughlin Community Centre on Keesing Street in Port Hedlandand at the Wanangkura Recreation Centre on Hamilton Road, South Hedland.
At 10.40am (WST), the cyclone was 170km north northeast of Port Hedland and 320km northeast of Karratha, moving south at 6km/h.
The red alert applies to areas between Pardoo and Whim Creek, including Port Hedland, which is Australia's biggest iron ore port and is already being buffeted by wind gusts of up to 120km/h.
Conditions in the town are expected to worsen during Tuesday and Wednesday.
Very destructive winds with gusts of more than 165km/h are likely to develop on the coast between Whim Creek and Pardoo on Wednesday as Rusty approaches the coast, the weather bureau says.
During Tuesday and Wednesday, very heavy rainfall is likely to lead to major flooding in the De Grey catchment.