Study lead author Michael McFarland, an associate professor of sociology at Florida State University, said the findings were "infuriating" because it was long known that lead exposure was harmful, based on anecdotal evidence of lead's health impacts throughout history.
Though the US has implemented tougher regulations to protect Americans from lead poisoning in recent decades, the public health impacts of exposure could last for several decades, experts told the Associated Press.
"Childhood lead exposure is not just here and now. It's going to impact your lifelong health," said Abheet Solomon, a senior programme manager at the United Nations Children's Fund.
Early childhood lead exposure is known to have many effects on cognitive development, but it also increases the risk for developing hypertension and heart disease, experts said.
"I think the connection to IQ is larger than we thought and it's startlingly large," said Ted Schwaba, a researcher at the University of Texas-Austin who studies personality psychology and was not part of the new study.
Schwaba said the study's use of an average to represent the cognitive impacts of lead exposure could result in an overestimation of impacts on some people and underestimation on others.
Previous research on the relationship between lead exposure and IQ found a similar impact, though over a shorter study period.
Bruce Lanphear, a health sciences professor at Simon Fraser University in Vancouver who has researched lead exposure and IQ, said his 2005 study found the initial exposure to lead was the most harmful when it comes to loss of cognitive ability as measured by IQ.
"The more tragic part is that we keep making the same mistakes again," Lanphear said. "First it was lead, then it was air pollution. Now it's PFAS chemicals and phthalates [chemicals used to make plastics more durable[. And it keeps going on and on.
"And we can't stop long enough to ask ourselves should we be regulating chemicals differently," he said.