"I think it's quite healthy that New Zealand has the debate, I suspect it won't be what it was when you looked at homosexual law reform in the'70s - I don't think it will be that dramatic."
Mr Key said the bill was likely to reach select committee stage and he thought there would be a lot of lobbying from those opposed and those in support of the bill.
Opponents had mobilised against the bill allowing gay and trans-gender couples to marry.
Conservative Party leader Colin Craig said he was planning a campaign on the advantages of heterosexual relationships and traditional family structures.
"I am keen to be part of a campaign to get out there on the issue. It would look intelligently at the differences between homosexual parenting and a Mum and a Dad," he said.
Mr Craig, whose party received 2.65 per cent of the vote in the general election, had committed part of his personal wealth to battling social policy in the past, such as Sue Bradford's anti-smacking bill.