Although numerous studies have linked ultra-processed foods to obesity, most have been observational, meaning they can’t prove that the foods directly cause weight gain.
Two previous trials found that adults consumed about 500 to 800 more calories per day when their diets were made up of ultra-processed foods than when they were made up of minimally processed foods.
Those studies were small and short; the larger of the two, conducted at the National Institutes of Health, included 20 participants who followed each diet for just two weeks.
Critics have argued that the results might have been different if the trials were longer, or if they included healthier ultra-processed foods.
The new study, though still small, was designed to address some of those concerns, said Samuel Dicken, a research fellow at University College London, and the lead author of the study.
Losing weight and body fat
Dicken and his colleagues recruited 55 participants, most of whom were women, ranging in age from their early 20s to their mid-60s, he said.
All had body mass indexes in the overweight or obesity ranges, and before the study, about two-thirds of their calories came from ultra-processed foods — more than the average for adults in Britain.
The researchers designed two diets and provided the meals.
Both diets met United Kingdom nutrition guidelines, with limited sugars, saturated fats and sodium.
One was composed mostly of minimally processed foods, like overnight oats, plain yoghurt, and scratch-made spaghetti Bolognese.
The other was mostly made up of ultra-processed foods considered healthy, like whole grain breakfast cereals, plant-based milk, flavoured yoghurt, and frozen lasagna.
Half the participants followed the minimally processed diet for two months, after which they returned to their normal diets for one month. Then they followed the ultra-processed diet for two months.
The other half followed the diets in the opposite order. All could eat as much or as little as they liked.
This kind of “crossover” study design is strong because it can show how each diet affected each participant, rather than averaging the responses across a group, said Brenda Davy, a professor of nutrition at Virginia Tech, who was not involved in the study.
Most of the participants lost weight on both diets.
On average, they lost more weight during the two months on the minimally processed diet — about 2kg compared with just 1kg on the ultra-processed diet.
Dicken and his colleagues estimated that if the weight loss had continued over one year, even as it naturally slows with time, it could have added up to 9% to 13% of body weight on the minimally processed diet, compared with just 4% to 5% on the ultra-processed diet.
The participants also lost more than twice as much body fat on the minimally processed diet than they did on the ultra-processed diet.
Fewer calories per bite, and fewer food cravings
It was somewhat surprising — and encouraging — that people lost weight on the ultra-processed diet, said Kevin Hall, a nutrition scientist and a co-author of the study.
This was likely because the study’s ultra-processed diet was more nutritious than the typical diets of the participants, he said. But participants still lost more weight on the minimally processed diet — a finding that aligns with those of previous studies.
That may be because minimally processed foods tend to have fewer calories per bite, said Filippa Juul, a nutritional epidemiologist at SUNY Downstate Health Sciences University who was not involved in the study.
And those foods generally have a harder texture that requires more chewing, so people may eat more slowly and consume fewer calories before feeling full, she said.
The participants also reported feeling like they had better control of food cravings on the minimally processed diet.
That’s surprising, Dicken said, because “when people lose weight, they tend to want to eat more”. Better craving control may help them keep the weight off longer, Dicken added.
Juul speculated that perhaps following a diet of mostly minimally processed foods may “reset cravings” and reduce “food noise”, helping people eat only when they are hungry.
A growing body of evidence
The study was relatively short, Walter Willett, a professor of epidemiology and nutrition at the Harvard T.H. Chan School of Public Health who was not involved in the study, wrote in an email.
“We need about a year, at minimum, for serious weight loss studies because early changes often reverse or don’t continue,” he added.
The researchers could not measure exactly what and when people ate, or how much they consumed, and the participants reported eating some foods besides those provided.
And most of the participants were women; men or children may have responded differently, Davy said.
Still, the study suggests that even if a person follows a healthy diet, there’s an added benefit to choosing minimally processed foods over ultra-processed ones, Juul said.
Evidence consistently suggests that diets high in ultra-processed foods can make it harder for people to stay at a healthy weight, she added.
Avoiding ultra-processed foods can be a challenge, though, since they are so ubiquitous and tend to be cheaper than minimally processed foods, Juul said. She advises choosing foods with recognisable ingredients.
Food manufacturers could help by making more minimally processed products that are convenient, affordable, and appealing, she added. “It’s a shift in food culture that’s needed.”
You don’t have to cut out ultra-processed foods entirely, Davy said. But try to cook at home as much as you can, focusing on fresh fruits and vegetables, lean proteins, and whole grains — “those things that we know are good for us”.
This article originally appeared in The New York Times.
Written by: Alice Callahan
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