"He started saying things like you are so hot and I was like, I will talk to you only if you will stop talking to me like that," she said.
Ms Friend said the man then pulled out a fire extinguisher and sprayed her in the face, news.com.au reports.
Another passenger was reportedly filming the whole incident.
CCTV inside the outlet captured the moment Ms Friend was doused in white foam.
"It was so fast, I inhaled it and I tasted it straight away," she said.
"(I thought) this is poison or something."
The young worker was taken to hospital where she was told she was lucky not to have lost her eyesight.
The men were reportedly of caucasian appearance and in their early 20s. The driver was skinny with brown scruffy hair.