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Home / World

Crypt of a pioneering, secular hospital reveals its secrets about Milan’s poor in the 17th century

Franz Lidz
New York Times·
28 Oct, 2025 05:00 PM5 mins to read

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The interior of the crypt of the Beata Vergine Anunciata, beneath the Ca’ Granda hospital in Milan, Italy. Bones that piled under a hospital over half a century shed light on the health and habits of some of the Renaissance era’s most impoverished people. Photo / LABANOF, University of Milan via The New York Times

The interior of the crypt of the Beata Vergine Anunciata, beneath the Ca’ Granda hospital in Milan, Italy. Bones that piled under a hospital over half a century shed light on the health and habits of some of the Renaissance era’s most impoverished people. Photo / LABANOF, University of Milan via The New York Times

A small city of the dead rests in a crypt that sprawls beneath Ospedale Maggiore, a public hospital in central Milan where, from 1637 to 1693, the corpses of some 10,000 patients were dumped and interred.

Established by the Duke of Milan in 1456, the facility, nicknamed Ca’ Granda, or Big Factory, had a singular mission: to provide assistance to the sick and injured, particularly the city’s working poor.

“It was Europe’s first known secular hospital,” said Folco Vaglienti, a historian at the University of Milan.

“Unlike the religiously affiliated institutions of the time, it welcomed people of any ethnicity or religion, marking a significant shift to a more universal approach to healing.”

In 2018, Mirko Mattia, a bioarchaeologist at the University of Milan, and a research team began sifting through the remains in the tombs.

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Since then they have been studying bones found in the crypt to better understand the health, diet and drug use of 17th-century Milan’s most impoverished people.

Ca’ Granda’s medical services, with pioneering treatments and therapies, were unrivalled throughout Europe.

Its four wings were built around a central church, Chiesa della Beata Vergine Annunziata, providing thousands of patients with specialised care in separate wards for broken bones, tuberculosis and other conditions.

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The hospital was equipped with its own infrastructure, including a sewer system, kitchens, a laundry, pharmacies and even an icehouse.

During the 1600s, a crypt was constructed under the church. Comprising 14 chambers, all about 2m tall, the sepulchres cover a surface area of more than 362sqm.

The burial vaults formed a sort of subterranean potter’s field.

After a granite lid was removed from one of the square holes in the church floor, bodies would be dropped into a vault of the brick-lined tombs.

Over time, the corpses accumulated and formed a funnel-shaped pile, called a talus cone.

These pyramids of remains grew over time, widening at the base and tapering to a point at the top. When a talus cone reached the ceiling and could not hold more bodies, a new underground vault would be used.

Unlike the lower layers, which held individual skeletons, the upper ones are a chaotic scramble of bones from many patients, along with a dark, soil-like residue of human tissue and microscopic bone dust.

The interior of the crypt of the Beata Vergine Anunciata, beneath the Ca’ Granda hospital in Milan, Italy. Photo / LABANOF, University of Milan via The New York Times
The interior of the crypt of the Beata Vergine Anunciata, beneath the Ca’ Granda hospital in Milan, Italy. Photo / LABANOF, University of Milan via The New York Times

This disarray was prompted by the crypt’s prolonged use and the hospital’s constant struggle to make room for more bodies.

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By combining Ca’ Granda’s patient records with the city’s Mortuorum Libri, a death register maintained at the State Archive since 1451, the research team discovered that the ossuary contains the remains of both men and women of all ages, from foetuses to the elderly.

Initial estimates suggest a high number of men, even in the care areas, who were allocated more space.

The crypt’s initial purpose was thwarted by its environment.

It was intended to be a holding area for corpses until they had decayed enough to be moved to a cemetery on the outskirts of the city.

Decomposition was hampered by high humidity and poor ventilation, the result of periodic flooding and the proximity to an aquifer.

Researchers during a survey in a sepulchral chamber beneath the Ospedale Maggiore, or Ca’ Granda, a hospital where the remains of about 10,000 patients were interred from 1637 to 1693, in Milan, Italy. Photo / LABANOF, University of Milan via The New York Times
Researchers during a survey in a sepulchral chamber beneath the Ospedale Maggiore, or Ca’ Granda, a hospital where the remains of about 10,000 patients were interred from 1637 to 1693, in Milan, Italy. Photo / LABANOF, University of Milan via The New York Times

Several factors led to the crypt’s closure in 1693: the unusual preservation of corpses in the cool, damp chambers; the challenges of retrieving them; and a powerful odour so repulsive that it caused nuns in the church to faint.

In 1697, a new burial place was opened, the Rotonda della Besana, which remained in use for half a century.

Researchers from the hospital and the University of Milan started surveying the tombs in 2010; excavation began eight years later.

Artifacts were sparse; in its time, Ca’ Granda was known for selling off the clothes and other belongings of the dead.

Mattia and his colleagues were surprised, then, to discover a cluster of five 400-year-old gold coins from Venice, Spain and France under the skeletons.

Mattia dismissed the possibility that the money came from a pocket or a purse; dead patients were stripped naked and wrapped in bedsheets before being lowered into the chambers.

He theorised that a travelling merchant, fearing theft while hospitalised, had swallowed the loot, a fatal attempt at concealment.

“What makes this strange is that Ca’ Granda only treated the indigent,” Mattia said.

“Before being admitted, patients underwent a triage process where they were required to provide documentation of their poverty and state, ‘I am poor.’”

Robert Mann, a forensic anthropologist at the University of Hawaii at Manoa who has examined the Ca’ Granda crypt but is not a direct participant in the study, argues that the site provides a more complete picture of the history and evolution of trauma, medical treatment, infectious diseases, and survival rates of that period.

Mattia said that the analysis of more than 300,000 of the two million or so bones in the crypt had revealed a patient population plagued by illness and malnutrition.

There was evidence of surgeries, autopsies and treatments using lead, mercury and other heavy metals.

There were also traces of drugs, including cannabis and coca, a psychoactive plant from the Americas.

Fossilized plaque on teeth offered clues to the patients’ diets, which included standard grains such as wheat, barley, sorghum, rice and millet.

It also featured potato starch, pointing to the early influence of New World foods, and spores from horsetails, a fern with green, nonflowering stems that can be toxic in large amounts.

The finding confirms contemporary accounts of people who, desperate from hunger, ate grass and died with mouths tinted green.

“We know more about ancient Roman plebeians than we do about the average 17th-century person,” Mattia said.

“History tends to focus on major political and military events, ignoring the lives of ordinary citizens.”

This article originally appeared in The New York Times.

Written by: Franz Lidz

Photographs by: LABANOF, University of Milan

©2025 THE NEW YORK TIMES

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