Rescue workers and doctors in Idlib said that the bombs alleged to have contained the chemicals did not detonate when they landed, but there was a strong smell of chlorine.
Dr Mohammed Ghaleb Tirani, the director of a field hospital in Sarmin, 10km southeast of Idlib city, treated six members of the Talib family, including three infants, found in a basement.
He said: "The children were foaming at the mouth, they were suffocating, then their hearts stopped. The parents had trouble breathing. We tried to treat them, but they died as well."
Muhammad Yazan, a local activist, told HRW that he had gone to where two barrel bombs had landed in a field on March 16 but there was no explosion. Soon afterwards, 30 civilians and 40 rebel fighters were affected and sought treatment in hospital. The Syrian Air Force is notorious for responding to rebel attacks by indiscriminate bombing of any area it believes to be in rebel hands. The barrel bombs normally contain explosives and scrap metal, but in this case there is strong evidence that chlorine gas canisters were employed.