Chisholm, who has a history of helping people, is leaving full-time work at TVNZ to spend more time with Elle and young sons Bede, 3, and Finn, 1, in the small town of Chatto Creek in Central Otago next year.
He said Chambers-Smith's social media call-out was a first — and he loved it. Going south would give him time to visit "the big sky and the place he loves".
"I loved Alice's audaciousness and cheekiness right from the get-go. I loved the fact she called me out. I read a couple of stories about her journey and thought, 'Alice could be any one of us'.
"Through no fault of her own she has brain cancer. I thought that if I'm in a position to be able to help her, I should. Also, running is good for my mind. It's helped me get out of a rut I've been in, so I thought if I could help Alice and help myself, it's a no brainer," says Chisholm.
"This run is also about doing something for me. Taking two days out to focus on me in a beautiful part of the world — but Alice is the real star."
Check out Instagram or the fundraising page: @catch_me_if_you_cancer on Instagram and give.everydayhero.com/nz/alice-tvnz-s-matt-chisholm-run-queenstown-for-brain-cancer.