The Spurs put six players in doube figures and were lead by 22 from Tim Duncan, while Manu Ginobli came off the bench to nail three of his four attempts from beyond the arc.
Adams was helpless to stop the offensive outburst, posting similar numbers to what he has recorded in the playoffs to date but unable to exert his influence defensively.
The Kiwi played 20 minutes and scored six points on three-of-four shooting, while also managing four rebounds and an assist. His contributions did come in meaningful minutes, being rested along side Kevin Durant and Russell Westbrook - who combined for 46 points - during garbage time in the fourth quarter.
That may portend greater game time on Sunday, when the Thunder defence must repeat their efforts from the successful games three and four. Even if Adams has only one game left in his maiden campaign, the 20-year-old will have surpassed all expectations after being drafted No 12 overall last year.
The centre has become an integral part of the Thunder's title challenge and, having been a relative later-comer to organised basketball, his steady improvements throughout this season promise a bright future.