Researcher and cardiologist Mark Richards said finding the precise biomarkers in the blood that indicate potential for future heart failure after a heart attack was like looking for a "needle in a haystack".
The teams' innovative method involved sifting through massive amounts of data to reveal six new, high-priority indicators of heart failure in patients with a heart attack which will be further researched.
"First, Associate Professor Mark Chan and his team in Singapore applied plasma proteomics - a term used to describe high-throughput analysis of plasma proteins - using a highly sensitive technique.
"This made it possible to reliably detect more than a thousand proteins in the blood of each patient, despite some proteins having very low levels," Richards said.
Richards said a second technology discovery was to cross-reference the proteins by analysing single heart cells one at a time, rather than the usual method of cells in bulk.
"Strong and reliable signals to identify those patients who may be unfortunate enough to incur heart failure following their heart attack, remains an urgent need."
Richards said it was hoped the new discovery could help those identified as high-risk get the right protective treatment to prevent heart failure.
