The crash occurred between the intersections with the State Highway 2 roundabout and Maraekakaho Rd on a stretch of road that is becoming a blackspot.
It was at least the third resulting in significant injury on the stretch of road in the past 10 weeks.
The speed limit had been lowered from 100km/h to 80km/h after a Hastings District Council speed limits bylaw review in 2018, and a man had been killed in a crash on the same stretch a year earlier.
An investigation into the crash is ongoing and police have asked for anyone who may have witnessed the crash to make contact.
Police are interested in hearing from anyone who may have witnessed the crash.
Anyone with any information can contact the police on 105, quoting file number 211104/5531.
Alternatively, information can be provided via Crime Stoppers on 0800 555 111.