The motorcyclist, who suffered serious injuries in the accident, was treated by St John ambulance staff at the scene before being taken to Auckland Hospital.
A spokesperson said police staff were now supporting the rider's family at hospital and the road had since re-opened to traffic.
Traffic was restricted for several hours through the area, with Auckland Transport tweeting the accident had closed the westbound lanes on Sylvia Park Rd.
Motorists were warned there was no access from Mt Wellington Highway.
The early morning crash had left the lanes blocked near the intersection with Mt Wellington Highway.
Auckland Transport said eastbound lanes, from Great South Rd, remained open.
Commuters were advised to avoid this route or expect delays.