The study, published in the Australian journal Healthcare Infection, involved 11 researchers who volunteered to use three different ways of hand-washing after they had been contaminated with a saline solution of E. coli bacteria from their own faeces.
In the first five to 10 seconds of the washing process, they found soap actually slowed the process of decontamination, which they considered was due to soap being a lubricant which affected the amount of friction.
Once the 20-second stage of the wash had been reached, the friction effect was restored because the soap had been washed off.
Soap only marginally improved the results at the end of the full 20-second friction wash.
But senior research fellow Dr Tom Miller, who led the study, said he was not suggesting people should avoid soap because it was useful for "visibly contaminated" hands.