Only they weren't mad, they loved it - albeit confused if it was about another cat or a human.
Many people said the post brought happiness amidst the Las Vegas killings, while also wanting NPR to provide more answers about Ramona.
And today that is just what NPR provided.
It turns out Ramona is the one-year-old daughter of NPR swing editor Christopher Dean Hopkins.
"We don't generally delete posts, so I tried to do it in a way that would be transparent," he explained.
"My job is to promote our good work, and I catastrophically failed in that last night."
Even though he does feel bad, Mr Hopkins hasn't completely shut down the idea of more Ramona stories.
"I suppose if people keep promising to pledge to NPR and it doesn't distract from the very good work our NPR journalists do, we'll see," he said.
