Lady Gaga and Amy Schumer are among the celebrities who have taken to social media to share their thoughts on a suspected "domestic terrorism" attack in San Bernardino, California.

Police responded to calls of a deadly mass shooting in a social services facility and spent hours working with a local SWAT team attempting to apprehend three men they suspected of killing 14 people.

Reports also suggest 17 people were injured in the attack, and many of them have been taken to a nearby hospital.

Lady Gaga was among the people watching the news unfold on TV and she took to Twitter to warn media outlets to be careful with their coverage.

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Actress Rashida Jones, Chrissy Teigen, Christina Applegate, Gloria Estefan and Blink 182 drummer Travis Barker were also among the stars who offered their thought and prayers to those caught up in the drama.

Amy Schumer, who has been at the forefront of America's gun control debate in recent months, took to Twitter as well.

The actress/comedienne joined her cousin, Senator Charles Schumer's gun campaign this year, after a shooting incident at a screening of her comedy Trainwreck in Lafayette, Louisiana in July.

-AAP