Farmers took up growing the Cavendish, which was immune to the fungus, in its place.
A new strain of the fungal disease, which affects the Cavendish, has developed and spread in recent years, threatening to wipe out the bananas we eat.
It has already spread across South Asia, Africa, the Middle East and Australia and scientists have said it is inevitable that sooner or later it will reach the Americas where most of the Cavendish crops are grown.
This time, scientists say, there is no immune variant waiting in the wings to replace the Cavendish, meaning genetic engineering is likely to be required to save the banana.
Dr Gert Kema, of the Wageningen University and Research Centre in the Netherlands, told the BBC: "We have nothing to replace the Cavendish right now.
"To carry on growing the same genetic banana is stupid.
"It is necessary that we improve the Cavendish through genetic engineering but parallel to that we must be finding genetic diversity in our breeding programmes."