Even under the best circumstances, stepping into a role previously held by someone considered to be a living god would have required a steep learning curve.
But less than 100 days after Lobsang Sangay was elected "Prime Minister" of the Tibetan Government in exile, the self-immolation of at least 11 Tibetans has confronted him with a remarkable challenge.
"It's an unprecedented trend, one after the other. You get these calls, early in the morning or late at night ... one more Tibetan has self-immolated," he said in an interview in his office in Dharamsala, home to the Tibetan community in India since the Dalai Lama fled Tibet in 1959.
"You don't really know anything. You don't have any images, or just two or three. And when you do see them, they are so horrifying. How can a human being be driven to such a desperate situation that they think it is better to give up their life?"
After his election, the Indian-born, American-educated Sangay was obliged to give up his life as a Harvard academic and move, physically and mentally, to the refugee community of Dharamsala to take up the struggle for "meaningful autonomy for Tibet".
His wife and child will join him, he says, once he has finished insulating his house and put in a new floor.
Sangay said he did not believe the immolations were being organised. Rather, he said, individuals were reacting to the repression and authoritarianism of the Chinese authorities.
Beijing had sought to blame people like him for what had happened.
The 43-year-old was elected on a platform of the "middle way" previously pursued by the Dalai Lama, who focused on trying to secure religious and cultural rights for the 5.5 million Tibetans inside Tibet, rather than independence from China.
The movement has largely bowed to the Dalai Lama's wishes, and Sangay said he did not think the immolations were a rejection of a moderate approach.
However, some younger Tibetans would prefer something more direct and urgent.
"I understand the frustration because there has been no breakthrough," said Sangay.
The Dalai Lama's unprecedented decision to split his religious and political roles means Sangay has an official role in the eyes of foreign governments and officials. But lobbying from China means few foreign leaders are likely to meet him as he will not be recognised as a religious leader, as the Dalai Lama is.
Many blamed South Africa's refusal last month to grant a visa to the Dalai Lama to enable him to attend the 80th birthday celebrations of Bishop Desmond Tutu on pressure from Beijing.
But Sangay recently made a visit to the US where he testified before a House of Representatives human rights commission, saying: "I think it's high time the international community realises the gravity and the urgency of the situation."
This month he will visit Britain and Europe. He has intentionally not asked for a meeting with British Prime Minister David Cameron or Foreign Secretary William Hague, aware of the controversy such a request would create, but he said he believed the British Government could be more vocal about human rights in Tibet and called on it to speak out over the immolations.
"A lot could be done," he said. "Every statement counts, every statement indicates that these lives are not lost in vain."