Her poem "On the Pulse of the Morning," which she recited in 1993 at President Bill Clinton's first inaugural, quickly sold hundreds of thousands of copies.
"What I have always wanted is to be of use," Angelou said Thursday. "I will not be abused. I will not be misused not willingly. But I will be of use. Anybody who is not of use is useless."
Angelou has been in frail health and is expected to only make a brief appearance at the awards dinner and ceremony in November.
A long list of nominees in the four competitive categories for the National Book Awards, which the Book Foundation presents, will be announced later this month.
E.L. Doctorow will receive an honorary medal for "contributions to American letters." Doctorow, 82, won the National Book Award in 1986 for "World's Fair" and was a finalist three other times. He is best known for the million-selling historical novel "Ragtime."
Previous winners of the National Book Award medal being given to Doctorow include Philip Roth, Arthur Miller and Elmore Leonard. Dave Eggers, Lawrence Ferlinghetti and National Public Radio's Terry Gross are among those who have received the Literarian Award.