Drivers and team members went through health screenings when they got to Texas Motor Speedway.
Many had already gone through similar screenings to get on chartered planes they boarded at dawn in Indianapolis — they were returning home after the race.
Crew members were required to wear face masks, and there was plenty of room for social distancing in the garage areas.
The massive grandstands that can seat more than 100,000 people were empty, and not because of extreme heat during the race. No spectators were allowed, as will also be the case for the next race on the road course at Indianapolis Motor Speedway on July 4.
"It's rotten that the fans aren't here. I wish everybody was here to celebrate," said Dixon, who extended his own record to 16 seasons in a row with a victory.
Dixon had the top speed during the two-hour practice session, and qualified second to start on the front row alongside Newgarden.
He led for a stunning 157 of the 200 laps, and had an earlier 6s lead over Newgarden wiped out by a caution for debris.
The race ended in drama with Dixon's main rival for the win, Rosenqvist, crashing out with just 10 laps to go as he tried to chase down the Kiwi.
What looked like a potential grandstand finish ended with relief for the five-time series champion.
Dixon went on to win the IndyCar title each of the three previous times he won the race at Texas.
- AP