The former Cessnock bricklayer had survived a huge scare to reach the semi-finals, prevailing 5-4 over Scot Ian White in a tense quarter-final after squandering a 4-1 lead.
But he was out-of-sorts and always on the back foot on Monday with Wright, sporting his trademark multi-colour mohawk and goatee, continuing his stellar form in the tournament to race to a 3-0 lead.
The Australian secured a break to get on the board with the fourth set but Wright hit straight back.
A fired-up Whitlock let out a scream of ``never say die'' after clawing back to 5-2 but Wright showed composure in his first world semi-final appearance to close it out and deny his opponent a chance to became Australia's first darts world champion since Tony David in 2002.
Van Gerwen and Lewis were contesting Monday's second semi-final.
- AAP