After rushing out to a quick 10-1 run in the third quarter, the Ferns managed to steady the ship and were ultimately too strong for the Welsh.
Te Paea Selby-Rickit led the scoring for New Zealand with 28 goals, shooting 90 per cent from the field, while Kelly Jury put in typically strong performance in defence.
Next up is a tricky match against the Malawi Queens and coach Janine Southby admitted the players need to keep their foot down.
"Unfortunately we got away (from the plan) in the second quarter which was disappointing," she said of the poorest period of the game.
"In the second half we came out with better connections and doing their job the way we know they can."
Southby said there were "some tired bodies" after two games in less than 24 hours. So the focus will be on recovery and getting ready to face a Malawi side whom Southby is anticiating will provide a tough challenge.