But he added: "One has to go with the full consensus of experts who know what they are doing and are there to do a job."
Select Committee chair Paul Hutchison said that MPs were advised by the expert panel that it was not possible to completely ban animal tests because these tests provided the most robust results.
Dr Hutchison said the legal highs were most likely to be used by young people and it was important to do the most rigorous testing possible to ensure the products would be safe.
Green Party MP Mojo Mathers said it was positive to have animal welfare recognised in the primary legislation - submissions on this issue were initially ruled out of scope. But she said that the bill still allowed animal testing, and "suitable alternatives" could be widely interpreted.
Animal testing was routinely used in New Zealand for medicines, but many submitters have questioned whether animal testing could be justified for proving the safety of recreational highs.
It is understood that the amendment was made because the animal rights issue was considered an obstacle to passing the law as soon as possible. The Psychoactive Substances Bill has been fast-tracked twice and must be in place before temporary bans on products lapse in August.
Many of the bill's amendments introduced restrictions that were similar to changes that Labour and Greens sought in the Alcohol Reform Bill.
Sponsorship and advertising was heavily restricted - retailers would banned from marketing the brands outside of their stores and manufacturers would not be able to advertise online, apart from on their own websites.
Dairies, groceries and petrol stations would be banned from selling legal highs, and communities would be able to decide the location and number of shops which sold synthetic drugs.