Emergency Services are at the scene of a serious crash on Takatu Rd at Tawharanui, near Warkworth.
The crash which involved a single vehicle happened just before midday.
One person has been critically injured and a second sustained moderate injuries.
The Auckland Westpac Rescue Helicopter has been called to transport the victims to hospital.
Takatu Rd between Tawharanui and Takatu Point has been closed to all traffic until the scene is made safe and the Serious Crash Unit completes their investigations.
The road is expected to remain closed for several hours.