The two new cases are isolated in Auckland, and health staff are following contact tracing procedures to assess the risk of further transmission.
While anybody could get the virus, the Health Ministry said "men who had sex with men" were at a greater risk.
"We are working closely with our community partners and have ensured they have resources and information to share with their communities."
If people had concerns about their health, the Ministry advised the, to contact their GP or call Healthline on 0800 611 116.
"If you experience skin changes or develop lesions or a rash then it's important to seek medical advice, even if you haven't travelled overseas recently. It may not be MPX, as many illnesses can cause similar symptoms, but it's still important to get it checked."
Information about monkeypox, including symptoms and public health advice, is available on the Ministry of Health website.