When she's away from home, Oprah admitted it is a challenge to "stay on point" but she does her best to maintain her regular routines.
She told Entertainment Tonight: "Maintaining that healthy routine when you're on the road [is important], because you know you want to hang out with the crew. You like to have a couple drinks after the show.
"No! You have to go to bed, get your sleep and get your rest. So it's staying on track, on point, when you're on the road. It's hard."
The media mogul doesn't make New Year's resolutions but likes to choose one word to define her plans for the year ahead.
She explained: "My word for this year is purpose.
"You know how you can't even figure out what you did in the year because your life's so full? So now I just go back and I look through my phone. So I was doing that on New Year's Eve, looking through the phone, and I was doing a lot of things, but I wasn't doing a lot of things with purpose.
"So my thing this year is, don't do anything unless you have an intention and a purpose behind it. Purpose."