The mum-of-two confirmed in September last year that she was expecting a second child with Scott in a 90-second Instagram video that ended with big sis Stormi kissing her mum's growing bump.
The Kylie Cosmetics founder has been open about wanting a big family, saying on her BFF Stassie Karanikolaou's #DoYourPart Instagram Live series in April 2020, "I want seven kids down the line, but not right now."
She added, "Pregnancy is just not a joke; it's a serious thing and it's hard."
The baby comes amid controversy for Jenner's boyfriend Scott, with the 30-year-old rapper facing a multi-million dollar lawsuit after last year's horrific Astroworld Festival tragedy.