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Home / Business

GlycoSyn tapping rich vein

BusinessDesk
5 Nov, 2014 04:00 PM2 mins to read

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Kifunensine is more valuable than gold. Photo / Sarah Ivey

Kifunensine is more valuable than gold. Photo / Sarah Ivey

New Zealand company GlycoSyn is seeking new global customers for kifunensine, a key ingredient in the manufacture of a drug for the treatment of rare genetic disorders that is worth 20 times more than gold per gram.

The drug research, development and manufacturing unit of Callaghan Innovation has sold more than $16 million of clinical grade kifunensine to a US-based biotech company in the past seven years. It is now marketing it to other pharmaceutical companies to boost the export revenue that funds the business.

Kifunensine is used as an ingredient to make drugs that inhibit background degradation of vital elements such as enzymes. As well as helping treat genetic disorders, it could also potentially change proteins in vaccines and have even wider use in the fight against viruses.

GlycoSyn general manager Paul Benjes said his unit was one of a handful of places worldwide that produce the complex ingredient and the only one that met the high quality standards required for GMP (good manufacturing practice) which gave it a fourfold premium over research grade material.

"We have a process patent over the way we make it, rather than the material itself, which is a barrier to competition, particularly in the US where the patent holds," he said.

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The drug material was originally developed by the former government-owned Industrial Research that Callaghan grew out of. It met a hitch when the original client walked away from the project.

"It left us in a precarious position of whether to continue to self-invest the development or pack it in," Benjes said. "I'm pleased now to say we elected to continue and came up with a very scaleable process that we patented in 2003 and another client came on the scene that has stayed with us ever since."

It won the commercial deal award in the KiwiNet Research Commercialisation awards in 2014 with the product. Business development manager Tony Davidson said a benefit from commercialising the product was that it established credibility for GlycoSyn's carbohydrate work worldwide and built relationships with international firms that could aid other Kiwi companies.

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Callaghan Innovation, which grew out of IRL to help Kiwi companies commercialise their innovations, makes about $8 million from GlycoSyn. That is half its budgeted commercial revenue, with taxpayers funding most of its 2014/2015 annual income of $244.8 million.

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