"The market's advance has been out of sync with weak earnings and economic trends," Jonathan Golub, chief US equity strategist at UBS, wrote in a note dated yesterday, according to Bloomberg. "Another spring break is likely to materialise and that now is a good time to begin dialling back on risk."
The Dow Jones Industrial Average shed 0.90 per cent, while the Nasdaq Composite Index fell 1.79 per cent.
The US economy grew at "a moderate pace" from late February to early April, according to the Federal Reserve's latest Beige Book.
"Most Districts noted increases in manufacturing activity since the previous report," the Fed said. "Particular strength was seen in industries tied to residential construction and automobiles, while several Districts reported uncertainty or weakness in defence-related sectors."
"Outlooks among respondents remained optimistic across sectors and Districts, with growth mostly expected to continue at the same or a slightly improved pace," according to the Fed.
In Europe, the Stoxx 600 Index dropped 1.5 per cent, while France's CAC 40 sank 2.4 per cent.
Germany's DAX Index slumped 2.3 per cent amid increased concern that the economic engine of Europe is beginning to falter under the weight of the euro region's ongoing debt crisis.
In an interview with the Wall Street Journal, Bundesbank President Jens Weidmann signalled the European Central Bank could reduce interest rates if economic and inflation data suggest it is warranted.
The UK's FTSE 100 Index fell 1 per cent as data from the Office for National Statistics showed the country's unemployment climbed by 70,000 to 2.56 million in the three months through February, the most since November 2011.