Research by the Centre for Ecology and Hydrology in June described the molluscs as "the top ranking threat to our natural biodiversity".
It predicted the Quagga mussels would arrive in the UK within the next five years.
Mr Knott said their spread is often because of human activity as adult Quagga mussels, who can produce one million eggs a season, attach themselves to boats.
"That's why it's so important for all water users to remember the motto 'clean, check, dry' when they pack up their equipment to help slow the spread," he explained.
"Quagga mussels are a prime example of why we need stronger controls on invasive species being brought into this country. Prevention is far cheaper and more effective than trying to control an infestation that's already established."
The mussels are believed to have originated in Ukraine. There is no effective way of completely removing their presence after they have been established in a resevoir.
A Defra spokesman said: "It is important that we take action to address the threats posed by invasive non-native species. They threaten the survival of our own plants and animals and cost the economy at least £1.8 billion a year.
"We will be working closely with interested parties and our agencies to reduce the risk of the Quagga mussel spreading any further. Users of our waterways can help with this by checking their equipment and keeping it clean and dry."
- Independent