On Saturday, Philadelphia Mayor Cherelle Parker said at least one other person, who was in a car, had also been killed, and 19 people had been wounded.
Speaking at a press conference, Parker warned the toll was “not etched in stone” and could yet rise.
“We have a lot of unknowns about who was where on the streets of this neighbourhood last night at the time of impact,” said the city’s managing director Adam Thiel, warning it could be days before the full toll emerged.
He said the impact area covered four to six blocks, and there was also debris in a “remote area where something happened with the aircraft”.
Mexican President Claudia Sheinbaum posted her condolences on social media platform X.
The US Federal Aviation Authority (FAA) said it was launching an investigation with the National Transportation Safety Board.
Both agencies are already probing the deadliest US air disaster in almost a quarter century, after a passenger jet operated by an American Airlines subsidiary collided with a Black Hawk helicopter on Wednesday.
The jet, with 64 people on board, was landing at Reagan National Airport in the Washington area – just miles from the White House – when it collided with a US Army helicopter on a training mission.
– Agence France-Presse