Martinelli, who faces a 12-year prison sentence if convicted in absentia, appeared in a Panama City court via video conference from Colombia, where he sought asylum last year.
“I am innocent, I am not responsible” the 73-year-old, who was president from 2009 to 2014, pleaded.
Odebrecht has admitted to paying US$59 million ($102m) in bribes during Martinelli’s tenure to win the tender for construction of Panama City’s metro, the modern coastal highway in the capital, and for the expansion of Panama’s international airport.
The prosecution argues that, although there is no evidence of payments being paid directly into Martinelli’s personal accounts, he was the final recipient of the funds and had “full knowledge of the illicit origin” of the money.
“This case is entirely political,” Carlos Carrillo, the former president’s lawyer, told AFP.
Another former president, Juan Carlos Varela, and two of Martinelli’s sons are also accused in the case but will be tried at a later date by the Supreme Court.
Martinelli sought asylum in Colombia last year to avoid arrest in a separate money laundering case over which he was sentenced to nearly 11 years imprisonment.
-Agence France-Presse