The era of planes going down because of engine failure, wind shear or midair collision has given way to state-of-the-art technology and vastly improved radar networks.
The grim story told by investigators probing this latest crash seems to fit a pattern for recent air disasters: The causes have been unusual, possibly unprecedented, making them hard to predict and tough to prevent.
Flying carries inherent risk, and some of the danger does emanate from the cockpit. Safety advocates and transport officials usually worry about pilot fatigue and distractions. But pilots almost never intentionally crash their planes, experts say.
"To do that in an airliner is just pretty darn rare," said Robert Benzon, who spent 27 years as a National Transportation Safety Board lead crash investigator. "You could tweak a database on suicide, and you'd get a lot of little planes. But airliners, not much would pop up at all."
If this crash is confirmed as deliberate, Benzon said it would be just the third suicide by airliner in memory, not counting the four planes hijacked by terrorists on September 11, 2001.
Flight 370's disappearance points to pilot action but that remains an unconfirmed theory.