She said there are 13 crime scenes where either deceased or injured people were found. She urged the suspects to turn themselves in.
Blackmore said police began receiving reports before 6am of stabbings on the First Nation community. More reports of attacks quickly followed and by midday police issued a warning that a vehicle reportedly carrying the two suspects had been spotted in Regina.
Police said the last information they had from the public was that the suspects were sighted in Saskatchewan's capital of Regina around lunchtime.
"If in the Regina area, take precautions & consider sheltering in place. Do not leave a secure location. DO NOT APPROACH suspicious persons. Do not pick up hitchhikers. Report suspicious persons, emergencies or info to 9-1-1. Do not disclose police locations," the RCMP said in a message on Twitter.
'He wouldn't show his face'
Doreen Lees, an 89-year grandmother from Weldon, said she and her daughter thought they saw one of the suspects when a car came barreling down her street early in the morning as her daughter was having coffee on her deck. Lees said a man approached them and said he was hurt and needed help.
But Lees said the man took off and ran after her daughter said she would call for help.
"He wouldn't show his face. He had a big jacket over his face. We asked his name and he kind of mumbled his name twice and we still couldn't get it," she said.
"He said his face was injured so bad he couldn't show it."
She said the man was by himself and "kind of a little wobbly".
"I followed him a little ways to see if he was going to be okay. My daughter said 'Don't follow him, get back here'."
'Horrific and heartbreaking' - Canadian PM
Canadian Prime Minister Justin Trudeau said the attacks are "horrific and heartbreaking".
"I'm thinking of those who have lost a loved one and of those who were injured," he said in a post on Twitter.
"We are closely monitoring the situation, and urge everyone to follow updates from local authorities. Thank you to all the brave first responders for their efforts on the ground."
The Premier of Saskatchewan, Scott Moe, has spoken out about the incident, labeling it "senseless violence".
"I want to offer my deepest condolences on behalf of the government and people of Saskatchewan to all of the family and friends of the victims of today's horrific attacks," he said.
"All of Saskatchewan grieves with the victims and their families.
It is thought the suspects may be driving a black Nissan Rogue.
In a post on Facebook, a woman shared a photo of a black Nissan Rogue and said: "My brothers vehicle that they took when they entered our home this morning in James Smith Cree Nation. We can care less about the vehicle but let these monsters be caught."
this is my brothers vehicle that they took when they entered our home this morning in James Smith Cree Nation, we can...
Posted by Tiaraa Twist on Sunday, September 4, 2022
'I lost a good neighbour'
The Canadian Press reported a Weldon resident said she was in her garden when she noticed emergency crews a couple of blocks away.
Shier said her neighbour, a man who lived with his grandson, was killed. She did not want to identify the victim out of respect for his family.
"I am very upset because I lost a good neighbour," she told the Canadian Press.
Tracy Marion, manager of the James Smith community convenience store and gas station told the Toronto Sun she was woken up, like many in the province, by the alerts blaring from her smartphone around 7am.
"I slept in, and I just woke up to all this news," she said.
Since then, she said she's seen the First Nation's usual calm has given way to a heavy police presence on the ground and the sound of helicopters in the air, but that access to and from the community remained open.
"There's too much happening, no one's thinking about that," the Toronto Sun reported.
The search for suspects was carried out as fans descended in Regina for a sold out annual Labor Day game between the Canadian Football League's Saskatchewan Roughriders and Winnipeg Blue Bombers.
The Regina Police Service said in a news release that with the help of Mounties, it was working on several fronts to locate and arrest the suspects and had "deployed additional resources for public safety throughout the city, including the football game at Mosaic Stadium".
The alert first issued by Melfort, Saskatchewan RCMP about 7am was extended hours later to cover Manitoba and Alberta, as the two suspects, Damien Sanderson, 31, and Myles Sanderson, 30, remained at large.
Both have black hair and brown eyes and may be driving a black Nissan Rogue.
Saskatchewan Crime Stoppers issued a wanted list last May that included Myles, writing that he was "unlawfully at large."
The Saskatchewan Health Authority said multiple patients were being treated at several sites.
"A call for additional staff was issued to respond to the influx of casualties," authority spokeswoman Anne Linemann said in an email.
Mark Oddan, a spokesman with STARS Air Ambulance, said two helicopters were dispatched from Saskatoon, Saskatchewan and another from Regina.
He said two carried patients to the Royal University Hospital in Saskatoon, while the third carried a patient to Royal University from a hospital in Melfort, a short distance southeast of Weldon.
Oddan said due to privacy laws, he could not disclose information about their ages, genders or conditions.
James Smith Cree Nation has declared a state of emergency.
