Based on the 2014 New Zealand-made mockumentary horror comedy film of the same name, the show follows the lives of four vampire roommates struggling to keep up with the duties and responsibilities of everyday life in their apartment in New York.
Waititi added a special shout out to fellow Kiwi and show creator Jemaine Clement, who he claimed to have tricked into doing the project in the first place.
"Suckaaaa!" he exclaimed.
The series has also been nominated for Outstanding Writing, Outstanding Production Design, Outstanding Casting, Outstanding Single-Camera Editing and Outstanding Sound Editing.
What We Do In The Shadows is available to stream on Neon.