"I've painted for years, probably like ten years now. It's my outlet," she said. "I jokingly said I'm going to be at Art Basel one day."
It's been an awe-inspiring year for Williams, who said she was "pinching myself, like what the heck am I doing here," at the Wimbledon final in July after a difficult pregnancy and childbirth.
She said her recent accomplishments on the court helped her persevere through the challenges of being a first-time mom.
"If I can be in the final less than a year (after giving birth), I'm OK to handle my little baby who's starting to have tantrums. I'm OK to handle this tantrum baby. I can do it. I can do it," she joked, speaking of her 15-month old daughter.
Last month, GQ magazine named her its 2018 Woman of the Year, featuring an image of Williams wearing a black bodysuit and Chanel belt. The headline crossed out "Men" and some fans took offense.
But Williams, who has been criticized for being too muscular, too strong and too outspoken throughout her career, said it was "really cool" and just another example of women breaking down barriers.
"This is a strictly men's thing but they broke and said, 'Let's also put a woman on (the cover) because this is a strong woman. She's just as strong as our men.'"
Art Basel Miami Beach, the prestigious extension of the annual contemporary art fair in Basel, Switzerland, has spawned dozens of other art shows around Miami over the years, along with star-studded parties days in advance.
Bono, Leonardo DiCaprio and rapper Cardi B, fresh from a split with rapper Offset, were all spotted making the rounds Wednesday night.
- AP