The Warriors had already been forced to shuffle their squad with injuries ruling fullback Apii Nicholls, five-eighth Patricia Maliepo and halfback Emily Curtain out.
The send-offs came with the side having already fallen 12-0 behind as the Raiders made a fast start in their bid for a first win of the season, which soon became a 16-0 lead after Ikenasio was sent off
The Warriors were resilient, though, and cut into the deficit just before halftime through winger Payton Takimoana.
The hosts showed their intent in the second half, with winger Lavinia Tauhalaliku scoring soon after the break. The Raiders pushed their lead out again, however, through a stunning try to fullback Elise Simpson and while Takimoana added two more tries to give the Warriors hope, the Raiders hung on for their first win of the season.
Warriors 16 (Payton Takimoana 3, Lavinia Tauhalaliku tries)
Canberra Raiders 20 (Jordyn Preston, Sereana Naitokatoka, Mackenzie Wiki, Elise Simpson tries; Zahara Temara con, pen)
HT: 16-4