Earlier, Tigers superstar Benji Marshall had turned in a playmaking masterclass to bring his side to the brink of victory.
With his playmaking partner Robbie Farah still sidelined due to suspension, Marshall took it upon himself to drag the Tigers out of their slump with a pivotal hand in all three of his side's tries.
The Rabbitohs lost star forward Sam Burgess to a knee injury early - with the initial diagnosis being a strained medial ligament which could mean up to a month on the sidelines.
The Tigers didn't escape unscathed either with another Englishman in Gareth Ellis limping off with a suspected fractured foot.
Fullback Tim Moltzen had an opening couple of minutes he'd love to bottle, with a 40-20 off the Tigers opening set backed up with a try off the ensuing scrum, Marshall bamboozling the defence as he schemed across field before finding his teammate in support.
The Rabbitohs were unable to capitalise on three straight penalties as they failed to get on the board before lock Michael Crocker was put on report for a high tackle on Moltzen which was similar to his hit on Brett Stewart in the 2007 grand final.
Having scrambled well in the first half, the Tigers would have been disappointed with the soft effort to concede Luke's first try seven minutes after the restart, but the home side regained the lead when Marshall set up Lote Tuqiri for a try in his first game of the year.
The game seemed over when Marshall and then Chris Lawrence put Blake Ayshford over for a 16-4 lead a lead they maintained until four minutes to go.
-AAP