Enrique insisted the tournament, which Barcelona has won in 2009 and 2011, was high on the club's priorities, given it had to win the Champions League to earn its place in Japan.
"To play in the Club World Cup gives the players opportunity for growth," he said.
"We came through a lot of hardship to get here. It's a very important title for the manager, the players, and the club president."
He singled out 31-year-old striker Robinho as a weapon in Guangzhou's attack, adding the Chinese club's five Brazilian players in general would need attention.
"Robinho still has a lot of years left in his career and is probably in the best stage of his career," Enrique said. "Perhaps he will only play for one half. One way or another, he's a player of top quality.
"They have skillful, young Brazilians who can score goals from midfield. We have to be careful about these players."
Barcelona center-half Gerard Pique stressed the unique challenges of the competition meant that although his club was favorite to lift the trophy, the players would need to adapt.
"Barcelona is a club that is always expected to win," Pique said. "During this tournament we play against some teams we don't normally play against. In that sense, we are in a very competitive environment. It's a different footballing culture, so as a player these are very precious experiences."
Guangzhou is on a 28-match unbeaten run stretching to May, shortly before Luiz Felipe Scolari took charge.
