Nuno was forced to bring in Nicolas Dominguez and Anthony Elanga in for suspended duo Morgan Gibbs-White and James Ward-Prowse, while Adam Wharton dropped to the bench for the first time this season in place of Will Hughes in Oliver Glasner’s attempt to end a seven-game winless run.
Eze was still waiting to open his account for the campaign and came a whisker away from doing so as he pounced on some sloppy possession and aimed his shot marginally the wrong side of a post which left Sels rooted to the spot.
Elliot Anderson looked to provide the spark for the hosts early on – he danced his way past three Palace defenders before stabbing a shot towards Henderson, which the ex-Forest keeper shoved out of play.
Anderson turned creator in the next phase and put in a delicious cross on to the head of Wood, who narrowly nodded wide.
The first chance of the second half fell for the visitors – Eze’s initial effort was saved by Sels but pushed into the path of Daichi Kamada, who was offside on the rebound.
Nottingham Forest broke the deadlock in the 65th minute.
Alex Moreno’s long ball forward was headed by Trevoh Chalobah into the path of Wood, who unleashed a first-time strike which squirmed beneath the diving Henderson.
Forest leaned on Sels once again to take the points after he tipped Jeffrey Schlupp’s curler behind in fantastic fashion and ensured a first home victory of the season.