Stokes' absence will have major implications for England's Test side against New Zealand, depriving them of an all-rounder who balances their side.
Without Stokes, England should be able to retain both Dan Lawrence and Ollie Pope in their Test XI, if they deem that four specialist bowlers are sufficient in early-season conditions. One of the two may yet bat at No 3 - the only way of accommodating both in a full-strength line-up when Stokes returns at five, with Joe Root at four.
England's batting situation is further complicated by opener Dom Sibley suffering a suspected broken finger, too. Should Sibley be fit, England's likeliest top six for the first Test at Lord's at this stage is Sibley, Rory Burns, Zak Crawley, Root, Pope and Lawrence. But Burns was dropped last winter and needs to score consistently in county cricket to retain his berth.
If England feel that they need a fifth bowler, then Chris Woakes could slot in at No 7, below the wicketkeeper - either Jos Buttler, depending on Rajasthan's IPL availability, or either Ben Foakes or James Brace. In this scenario, England would have to leave out one of Sibley, Burns, Crawley, Pope and Lawrence.
Stokes now faces a race to be Test-match fit for England's summer opener against India, which begins at Trent Bridge on August 4. England play five Tests against India, but, with the Hundred launching on July 21, Stokes could now go into that series without any first-class cricket in five months, going back to England's 3-1 defeat in India last winter.