This miss was described by his camp as an "oversight" due to his staying in Samoa rather than returning to his base.
The use of performance-enhancing drugs in boxing is an increasingly big issue.
Russian Alexander Povetkin will appear on the undercard of the Joshua v Parker main event despite failing two tests in 2016. On March 3, WBC heavyweight world champion Deontay Wilder will face Luiz Ortiz in a title defence in New York despite Ortiz failing two tests in four years.
On the weekend before Joshua v Parker, Australian Lucas Browne will take on Englishman Dillian Whyte in London. Both men have failed drugs tests in the past, with Browne stripped of his WBA "regular" world title as a result.
Eddie Hearn, Joshua's promoter, has insisted British boxing at least has the problem of performance-enhancing drugs contained.
"I really believe it's a problem that's being solved," Hearn told Britain's Independent last month.
"Where we are now compared to two or three years ago is night and day.
"The main problem, I feel, is in other countries but Britain is doing well. We have the Ukad [United Kingdom Anti-Doping] random testing. It means Joshua was tested six times in the build-up to his last camp. Other fighters are getting knocks on the door at 3am for testing.
"But in America, or other countries, there is no testing at all other than around the event, although that is changing."
For Higgins, the testing is important because the fight game is "the purist form of contest. It's not a team sport, you can't rely on team-mates, there's nowhere to hide, it's just you versus the other guy".