Hearn said while Fa will approach the bout like a man with nothing to lose, the opposite is true for Parker.
"A loss would be catastrophic for Joseph's career," he said, pulling no punches. "It will come down to his hunger... he has to demolish Junior Fa this weekend."
If he fulfils that end of the bargain, Hearn said it will be a busy year for Parker.
"He needs to fight three times this year," Hearn said.
Matchroom will parlay Parker's ("and, weirdly, David Higgins'") popularity in the United Kingdom into a high-profile, eyeball-harvesting fight with colourful Dereck Chisora, possibly as early as late-April.
If he wins those two fights, Hearn expects Parker's to be the mandatory WBO challenger.
Anthony Joshua, who is set to fight Tyson Fury for the right to be called undisputed world heavyweight champion, is the current WBO belt holder. Oleksandr Usyk and Joe Joyce are ranked two and three in the WBO and are due to fight this year.
Hearn says other potentially tasty matches for Parker, providing he keeps winning, include possible rematches with Dillian Whyte and/ or Andy Ruiz Jr. He said he believed Parker needed only "15 more seconds" to beat Whyte in their match and that his win against Ruiz Jr was "underrated".
"Joseph Parker is a cast-iron top 10 heavyweight in the world and I believe he's top five," Hearn said.
"If he struggles with Junior Fa, that [damages him]. He needs to make a statement."