Whelan said structural effects on some buildings will cause challenges.
"The reports we're seeing indicate that less than half of one per cent of commercial buildings in Wellington City have experienced significant structural damage. That's a tremendously resilient result overall."
He said cafes, bars and retailers were among the first to open their doors after the quake hit on Monday.
"Hotels in the city are all open, we have multi-day conferences at the Michael Fowler Centre, TSB Bank Arena and Shed 6, and performances at venues throughout Wellington."
Whelan said that a short-term effect on Wellington's economic performance is expected.
"Following the last decent shake in 2013, business confidence in Wellington recovered rapidly.
"Longer-term, the events of this week have reinforced the argument for further investment in Wellington's infrastructure."
Whelan said earthquakes are "a fact of life in New Zealand".
"Wellington's seismic resilience has developed over many decades, and continues to improve, as this week has demonstrated.
"Damage to the city has been limited, nobody was seriously hurt, transport networks are up and running and Wellington was largely back in business within 48 hours."