Diversions are in place and motorists are advised to expect delays while emergency services work at the scene.
The Serious Crash Unit had been advised and an investigation into the crash was under way.
Fire and Emergency New Zealand shift manager Simon Lyford said FENZ assisted police at the scene, while also working to extinguish a vegetation fire caused by the accident.
Three appliances attended the scene, including two from Bluff and a tanker from Invercargill, Lyford said.