One person has died in a house fire in Māngere, South Auckland.

Emergency services were called to the fatal blaze on Ettrick Place in Māngere East shortly after 5am today.

Fire and Emergency New Zealand (Fenz) assistant area commander Craig Monrad confirmed one person who had been unable to get out of the house had died.

Monrad said by the time his crew arrived at the scene the fire was well evolved and there was no chance firefighters could get inside for a rescue.

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"It is unfortunate. It highlights the importance of having an escape plan and being able to get out of a house on fire quickly."

He said all other family members managed to evacuate the house safely.

"Unfortunately, because of the location of the fire, the person who is deceased was unable to evacuate," Monrad said.

Fire crews managed to put out the fire quickly and were working to investigate the cause of the blaze.

A St John spokeswoman said two patients were assessed with minor injuries and one other person was in a moderate condition.

"Patients did not require transport to hospital," the spokeswoman said.

Five fire trucks with 20 firefighters were at the scene, along with police. Three St John ambulance crew were also at the scene.