A two-vehicle crash on the Harbour Bridge is blocking a lane and slowing traffic on the Northern Motorway.

The collision is blocking lane two for traffic heading north.

Motorists have been advised to expect delays with traffic heavy through to Northcote Rd and again from Tristram Ave to Upper Harbour Highway.

A police spokeswoman said it was called at 4.20pm to a two-car crash near the Stafford Rd off-ramp.

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Police had just arrived on the scene, she said.