The researchers explored how genetically different populations of the main microbe used in the fermentation process during wine-making - the Saccharomyces cerevisiae yeast - affected the flavour and aroma of a wine.
Much of the character of a wine comes from chemical compounds produced as byproducts during fermentation, when sugars from the grapes are converted into alcohol.
Using sauvignon blanc grapes, they found that concentrations of 39 different compounds derived from yeast during the fermentation process affected the flavour and aroma of wine - and 29 of those compounds varied depending on which region the yeast originated from.
"It's sometimes been speculated that microbes play an important role, and this is now confirming that," Ms Knight said.
"For winemakers, this gives them a better idea of what it is that makes their wine special - and by showing that microbes are important, it keeps in their mind that they need to be aware of what's in their vineyard, and how to manage it."
Dr Goddard said the findings, published in the journal Scientific Reports, could apply beyond winegrowing.
"With a better understanding of the forces driving microbial population and community differentiation, food and agriculture sectors can develop systems to better control and manage these communities, helping to conserve the regional identity of products and crop health and productivity."