But of greater concern was that the polymer filter melted slightly during use and released formaldehyde cyanohydrin, a toxic substance which could be fatal to humans. The compound is metabolised in the liver and broken down into formaldehyde and cyanide.
"This study has shown that the iQOS system may not be as harm-free as claimed and also emphasises the urgent need for further safety testing as the popularity and user base of this product is growing rapidly," the study concluded.
University of Otago public health and marketing Professor Janet Hoek said the findings led her to question whether it really was a "reduced harm" product as claimed by the manufacturers.
If users inhaled more frequently as it was suggested, it was likely they would "increase their nicotine intake and exposure to harmful compounds present in the inhaled aerosol", she said.
She said those who had tried unsuccessfully to quit smoking were better off considering e-cigarettes.
Auckland University National Institute for Health Innovation programme leader Associate Professor Natalie Walker agreed e-cigarettes were a better option for those trying to quit because they did not contain tobacco.
But, when smokers had tried repeatedly to quit, even using e-cigarettes, it could be a last resort.
"Heat-not-burn devices are not without harm. However, they are less harmful than smoking cigarettes [which have over 4000 harmful chemicals in the smoke]," she said.