The Cruze is already Holden's second-best-selling car behind the Commodore, and a rival to the market-leading Mazda3 for passenger car leadership.
In its original ANCAP test in 2009, the CD Cruze sedan scored 35 points of a possible 37, with 15 points of a possible 16 in occupant protection.
ANCAP commented that the Cruze body held its shape well in the 64km/h offset crash test and, after the crash, all doors could be opened with normal effort.
The worst rating for any particular element of the crash tests was an "acceptable" for chest protection for the front seat occupants and the lower legs of the front seat passenger.
Results from the tough side impact pole test were all rated as "good".
Built on General Motors' global Delta II small-car platform, the Cruze is fitted with six airbags - including driver and front passenger, front side impact and side curtain airbags - electronic stability control (ESC), anti-lock brakes, electronic brake-force distribution, traction control and a collapsible pedal assembly system.
Announcing the result, GM Holden chairman and managing director Mike Devereux said Holden had always been confident in the real-world safety capabilities of the Cruze.
"We knew we were building an extremely safe car," he said. "The high level of safety features is just one of the many reasons Cruze has been so well received in this country, making it Australia's third-best-selling passenger car in 2011 with just one body style.
"With stunning Cruze hatch styling, a high level of standard features and now this safety stamp of approval, we believe we're on to a real winner.
"We can't wait to get the hatch version into our showrooms next month and into customers' hands," said Devereux.